The dad from Malcolm in the Middle plays a high school chemistry teacher which, after learning he has inoperable lung cancer, starts to cook meth to secure his family's future. It is franking greatness. Great drama mixed with super-dark comedy. I recommend it.
That is what someone else said...I've never seen Weeds but all the reviews say it is different enough, and all have been positive. It's on Sunday nights on AMC. I'd suggest torrenting the first two episodes, they are great.